Estrogen + Progestin Combinations Drug Class Overview, Drugs, Uses, Side Effects, and Interactions

Estrogen and progestin combination is a group of drugs that contain that are normally hormones found in the female’s’ body. The hormones are used in regulation of menstrual cycles in the reproductive age and also development of female sex characteristics. These two medicines when combined are used to compensate for the low estrogen production during menopause. A combination of estrogen and progestin is used in prevention of pregnancy occurrence. When preventing pregnancy, the drugs work by thickening the walls of the uterus and this makes it difficult for the sperm to reach the ovum for the purpose of fertilisation. In addition to this, they make the lining of the uterus unsuitable for the egg development.

Estrogen + Progestin Combinations Drugs

There are various drugs found in this class of medications. They are available inform of tablet and tablet chewable. US brand names

Other trade names

Estrogen + Progestin Combinations Uses

Estrogen and progestin combination drugs are used to treat osteoporosis, relief of vaginal or vulvar atrophy. They are also used to make up for less estrogen production. This class of drugs is used in treatment of heavy or irregular menstrual periods. They may also be used for other purposes that the doctor may recommend. In prevention of pregnancy, progesterone is responsible for thickening of the uterine walls making it difficult for the fertilisation to take place. The drugs may also act on the uterine wall stimulating unsuitable conditions for the egg development. Some of the signs of heavy periods include menstrual pain and abnormal bleeding.

Estrogen + Progestin Combinations Side Effects

Despite the many benefits from estrogen and progestin combination, various patients have complained of undesired effects resulting from these drugs. Do not stop using your medication without consulting your doctor. Changes in menstrual cycle and breast tenderness are some of the common side effects resulting from this class of drugs. All the same, it is highly recommended to see your doctor if any of the following serious signs and symptoms occurs.

  • Severe headache
  • Fainting and dizziness
  • Coughing up blood
  • Pain in the legs
  • Bulging of the eyes
  • Feeling weak
  • Fever
  • Concentrated urine
  • Abnormal bleeding
  • Heavy bleeding

Very serious side effects

Estrogen + Progestin Combinations Interactions

Before the administration of estrogen and progestin combination, it is advisable to consider the following. Patients with allergic reactions to any medicine in this class or any other allergy should inform their doctors. Pregnant or breast feeding mothers should not use this drug. Cigarette smoking results in severe adverse effects when taking this combination. The effects may include heart attack, blood clot and stroke among others. The use of various types of medications along with this class of drugs is not recommended. It is advisable to inform your doctor about the other kind of medicines you are using in order for him/her to advise you accordingly. The drugs are