Pamelor is a second generation antidepressant drug. It is an FDA approved medicine used both in the US and UK to treat cases of major depression. Pamelor is also used for the treatment of other conditions and aids smokers to quit. Pamelor, like other antidepressants, may result in suicidal thoughts, especially in young patients prescribed for the first time. Pamelor is also known to produce severe side effects so patients are advised to be on the lookout for these symptoms and report them to a doctor at once.