Methylprednisolone is a corticosteroid used to relieve the symptoms of inflammatory conditions such as arthritis, lupus, psoriasis, ulcerative colitis, and more. Methylprednisolone works by preventing substances from inducing inflammation in the body, specifically by downregulating the effects of the immune system. Common side effects include stomach upset, dizziness, and anxiety.Methylprednisolone is a steroid that is used to prevent the release of substances in the body that cause inflammation. The drug is also used to treat several inflammatory conditions such as psoriasis, ulcerative colitis, allergic disorders, gland disorders and other conditions that affect the lungs, stomach, eyes, skin and blood cells. Methylprednisolone works by decreasing the patient's immune system's response to reduce symptoms such as swelling allergic type reactions and pain. The drug may be used with other medicines for various diseases. Patients are advised not to extend the dosage as prescribed by the pharmacist. Using the drug more than recommended can be harmful to your body.